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What are the possible side effects of HCG?

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• an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
• pain, warmth, redness, numbness, or tingling in an arm or leg (which may indicate a blood clot); or
• confusion, severe dizziness, or severe headache (which may indicate a blood clot in the head).

A small percentage of female patients treated with HCG have developed the ovarian hyperstimulation syndrome (OHSS), especially after the first cycle of therapy. Symptoms of OHSS include severe pelvic pain, swelling of the hands or legs, abdominal pain and swelling, shortness of breath, weight gain, low urine output, diarrhea, and nausea or vomiting. OHSS can be fatal. Notify your doctor immediately or seek emergency medical attention if you develop any of these symptoms.

Other side effects may also occur. Notify your doctor if you experience

• headache;
• irritability;
• restlessness;
• depression;
• fatigue;
• fluid retention (edema);
• breast tenderness or swelling;
• pain, swelling, or irritation at the injection site;
• early or premature puberty.

Treatment with HCG increases the likelihood of multiple births. Multiple births carry additional risk both for the mother and for the babies.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect HCG?

It is not known whether other medications will interact with HCG. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products.

Where can I get more information?

Your pharmacist has additional information about HCG written for health professionals that you may read.

What does my medication look like?

HCG is available with a prescription under the several brand names. Generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

• Novarel 10,000 Units powder for injection
• Pregnyl 10,000 Units powder for injection
• Profasi 5,000 Units powder for injection
• Profasi 10,000 Units powder for injection
• Ovidrel 250 mcg powder for injection

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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